Syntheses of Analgesics. XXXII

The COPD Pipeline XXXII.

COPD accounts for approximately 26 million prescriptions per year in the United States. According to an analysis by Novartis R&D, the U.S. market for COPD drugs was running at $11.8 billion in 2012, 70% of that fi gure being almost equally divided between a LAMA, namely tiotropium, and the 2 ICS/LABA combinations. Th eir estimate is that the COPD drug market will increase by 24.4% to $14.8 bill...

of Economic Literature , Vol . XXXII ( December 1994 )

Xxxii. the Heat-stable Peroxidase of Bacteria

Xxxii Malignant Mesothelioma of the Pleura

nodule of tumor tissue which grossly compressed the adjacent normal appearing liver substance. Gros8 Pathological Diagnoses: 1. Bronchogenic carcinoma, right upper lobe bronchus with metastases to both lungs, hilar lymph nodes, and nodule in the liver. 2. Generalized arteriosclerosis. 3. Arteriolar sclerosis, kidneys. 4. Nodular hyperplasia, prostate. 5. Cholelithiasis. With hematoxylin and eos...

Opioid Analgesics

Intensive research on the neurobiology of pain over the past two decades has revealed many receptors, ion channels and enzymes with potential as novel targets for development of a new generation of analgesic agents. However, despite large investment in preclinical and clinical development of small molecules and biologics as potential novel pain therapeutics, very few have reached the clinic. He...